Anathema

[ uh-nath-uh-muh ]

noun

something or someone that one strongly dislikes
a formal curse by a pope or a council of the Church, excommunicating a person or denouncing a doctrine

Examples of anathema in a sentence:

After the world learned of his heinous crimes, the dictator was considered an anathema.
The epidemic which killed dozens of small children was an anathema to the residents of the town.